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Index > Protein center > Cd300a(Gene name) > Mouse
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  • Cd300a (Gene name),
  • CMRF35-like molecule 8 (Protein name ),  CLM8_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Cd300a(Clm8;Lmir1;Mcpir1);
    Protein name:
    CMRF35-like molecule 8(CLM-8);
    Alternative:
    Leukocyte mono-Ig-like receptor 1;CD300 antigen-like family member A;Myeloid-associated immunoglobulin-like receptor 1(MAIR-1;MAIR-I);Mast cell-derived paired immunoglobulin-like receptor 1;
    CD:
    CD300a;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Upon tyrosine-phosphorylation, interacts with PTN6/SHP-1 and PTPN11/SHP-2 and INPP5D.
    Function:
    Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    318
    Sequence:
    50:
    MTQLASAVWL | PTLLLLLLLF | WLPGCVPLHG | PSTMSGSVGE | SLSVSCRYEE | 
    100:
    KFKTKDKYWC | RVSLKILCKD | IVKTSSSEEA | RSGRVTIRDH | PDNLTFTVTY | 
    150:
    ESLTLEDADT | YMCAVDISLF | DGSLGFDKYF | KIELSVVPSE | DPVSSPGPTL | 
    200:
    ETPVVSTSLP | TKGPALGSNT | EGHREHDYSQ | GLRLPALLSV | LALLLFLLVG | 
    250:
    TSLLAWRMFQ | KRLVKADRHP | ELSQNLRQAS | EQNECQYVNL | QLHTWSLREE | 
    300:
    PVLPSQVEVV | EYSTLALPQE | ELHYSSVAFN | SQRQDSHANG | DSLHQPQDQK | 
    318:
    AEYSEIQKPR | KGLSDLYL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CLM-8
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    ELISA Kit for Mouse CLM-8
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    96T
    CLIA Kit for Mouse CLM-8
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    CLIA Kit for Mouse CLM-8
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    U9365r
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    CLIA Kit for Mouse CLM-8
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    Packing:
    96T
    Polyclonal Antibody for Mouse CLM-8
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    Packing:
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    Packing:
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    Monoclonal Antibody for Mouse CLM-8
    Monoclonal Antibody for Mouse CLM-8
    Monoclonal Antibody for Mouse CLM-8
    Protein for Mouse CLM-8
    Protein for Mouse CLM-8
    Protein for Mouse CLM-8

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    References
    1. 1.
      "Identification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cells."
      Kumagai H. , Oki T. , Tamitsu K. , Feng S.-Z. , Ono M. , Nakajima H. , Bao Y.-C. , Kawakami Y. , Nagayoshi K. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Kawakami T. , Kitamura T.
      Biochem. Biophys. Res. Commun.307:719-729(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;PHOSPHORYLATION;INTERACTION WITH PTPN6; PTPN11 AND INPP5D
      strain: CBA/J.
      tissue: Mast cell.
    2. 2.
      "Paired activating and inhibitory immunoglobulin-like receptors, MAIR-I and MAIR-II, regulate mast cell and macrophage activation."
      Yotsumoto K. , Okoshi Y. , Shibuya K. , Yamazaki S. , Tahara-Hanaoka S. , Honda S. , Osawa M. , Kuroiwa A. , Matsuda Y. , Tenen D.G. , Iwama A. , Nakauchi H. , Shibuya A.
      J. Exp. Med.198:223-233(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);FUNCTION;GLYCOSYLATION;PHOSPHORYLATION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;MUTAGENESIS OF TYR-237
      tissue: Fetal liver.
    3. 3.
      "CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation."
      Chung D.-H. , Humphrey M.B. , Nakamura M.C. , Ginzinger D.G. , Seaman W.E. , Daws M.R.
      J. Immunol.171:6541-6548(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: C57BL/6.
    4. 4.
      "Molecular cloning of an NK inhibitory receptor-related gene expressed in a mouse microglial cell line, Ra2."
      Yoshimoto M. , Sekine S. , Yazaki M. , Sawada M.
      Submitted (2001-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    5. 5.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    8. 8.
      "The inhibitory receptor IRp60 (CD300a) is expressed and functional on human mast cells."
      Bachelet I. , Munitz A. , Moretta A. , Moretta L. , Levi-Schaffer F.
      J. Immunol.175:7989-7995(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY
    9. 9.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-303;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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